L Businaro

Affiliations

Institute for Photonics and Nanotechnology, Italian National Research Council, 00156, Rome, Italy.

Publications (21)

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments.

Journal of visualized experiments : JoVE

Avec: Adele De Ninno , Francesca Romana Bertani , Annamaria Gerardino , Giovanna Schiavoni , Martina Musella , Claudia Galassi , Fabrizio Mattei , Antonella Sistigu , Luca Businaro

Crosstalk and communication of cancer-associated fibroblasts with natural killer and dendritic cells: New frontiers and unveiled opportunities for cancer immunotherapy.

Cancer treatment reviews

Avec: Simone Ielpo , Francesca Barberini , Farnaz Dabbagh Moghaddam , Silvia Pesce , Chiara Cencioni , Francesco Spallotta , Adele De Ninno , Luca Businaro , Emanuela Marcenaro , Roberto Bei , Loredana Cifaldi , Giovanni Barillari , Ombretta Melaiu

Discovering the hidden messages within cell trajectories using a deep learning approach for in vitro evaluation of cancer drug treatments.

Scientific reports

Avec: A Mencattini , D Di Giuseppe , M C Comes , P Casti , F Corsi , F R Bertani , L Ghibelli , L Businaro , C Di Natale , M C Parrini , E Martinelli

A Bayesian Approach for Coincidence Resolution in Microfluidic Impedance Cytometry.

IEEE transactions on bio-medical engineering

Avec: Federica Caselli , Adele De Ninno , Riccardo Reale , Luca Businaro , Paolo Bisegna

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer.

Nature communications

Avec: Luigi Racioppi , Erik R Nelson , Wei Huang , Debarati Mukherjee , Scott A Lawrence , William Lento , Anna Maria Masci , Yiquin Jiao , Sunghee Park , Brian York , Yaping Liu , Amy E Baek , David H Drewry , William J Zuercher , Francesca R Bertani , Luca Businaro , Joseph Geradts , Allison Hall , Anthony R Means , Nelson Chao , Ching-Yi Chang , Donald P McDonnell

A simple electrical approach to monitor dielectrophoretic focusing of particles flowing in a microchannel.

Electrophoresis

Avec: Riccardo Reale , Adele De Ninno , Luca Businaro , Paolo Bisegna , Federica Caselli

IL-33 Promotes CD11b/CD18-Mediated Adhesion of Eosinophils to Cancer Cells and Synapse-Polarized Degranulation Leading to Tumor Cell Killing.

Cancers

Avec: Sara Andreone , Francesca Spadaro , Carla Buccione , Jacopo Mancini , Antonella Tinari , Paola Sestili , Adriana Rosa Gambardella , Valeria Lucarini , Giovanna Ziccheddu , Isabella Parolini , Cristiana Zanetti , Maria Teresa D'Urso , Adele De Ninno , Luca Businaro , Claudia Afferni , Fabrizio Mattei , Giovanna Schiavoni

Accelerating the experimental responses on cell behaviors: a long-term prediction of cell trajectories using Social Generative Adversarial Network.

Scientific reports

Avec: Maria Colomba Comes , J Filippi , A Mencattini , F Corsi , P Casti , A De Ninno , D Di Giuseppe , M D'Orazio , L Ghibelli , F Mattei , G Schiavoni , L Businaro , C Di Natale , E Martinelli

Rapid Assessment of Susceptibility of Bacteria and Erythrocytes to Antimicrobial Peptides by Single-Cell Impedance Cytometry.

ACS sensors

Avec: Cassandra Troiano , Adele De Ninno , Bruno Casciaro , Francesco Riccitelli , Yoonkyung Park , Luca Businaro , Renato Massoud , Maria Luisa Mangoni , Paolo Bisegna , Lorenzo Stella , Federica Caselli

Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca

Lab on a chip

Avec: Flavia Mazzarda , Annunziata D'Elia , Roberto Massari , Adele De Ninno , Francesca Romana Bertani , Luca Businaro , Gaia Ziraldo , Veronica Zorzi , Chiara Nardin , Chiara Peres , Francesco Chiani , Abraham Tettey-Matey , Marcello Raspa , Ferdinando Scavizzi , Alessandro Soluri , Anna Maria Salvatore , Jun Yang , Fabio Mammano

High-throughput label-free characterization of viable, necrotic and apoptotic human lymphoma cells in a coplanar-electrode microfluidic impedance chip.

Biosensors & bioelectronics

Avec: Adele De Ninno , Riccardo Reale , Alessandro Giovinazzo , Francesca R Bertani , Luca Businaro , Paolo Bisegna , Claudia Matteucci , Federica Caselli

High-throughput analysis of cell-cell crosstalk in ad hoc designed microfluidic chips for oncoimmunology applications.

Methods in enzymology

Avec: Arianna Mencattini , Adele De Ninno , Jacopo Mancini , Luca Businaro , Eugenio Martinelli , Giovanna Schiavoni , Fabrizio Mattei

From Petri Dishes to Organ on Chip Platform: The Increasing Importance of Machine Learning and Image Analysis.

Frontiers in pharmacology

Avec: Arianna Mencattini , Fabrizio Mattei , Giovanna Schiavoni , Annamaria Gerardino , Luca Businaro , Corrado Di Natale , Eugenio Martinelli

High-throughput electrical position detection of single flowing particles/cells with non-spherical shape.

Lab on a chip

Avec: Riccardo Reale , Adele De Ninno , Luca Businaro , Paolo Bisegna , Federica Caselli

The influence of spatial and temporal resolutions on the analysis of cell-cell interaction: a systematic study for time-lapse microscopy applications.

Scientific reports

Avec: M C Comes , P Casti , A Mencattini , D Di Giuseppe , F Mermet-Meillon , A De Ninno , M C Parrini , L Businaro , C Di Natale , E Martinelli

Oncoimmunology Meets Organs-on-Chip.

Frontiers in molecular biosciences

Avec: Fabrizio Mattei , Sara Andreone , Arianna Mencattini , Adele De Ninno , Luca Businaro , Eugenio Martinelli , Giovanna Schiavoni

Electro-Optical Classification of Pollen Grains via Microfluidics and Machine Learning.

IEEE transactions on bio-medical engineering

Avec: Michele DaOrazio , Riccardo Reale , Adele De Ninno , Maria A Brighetti , Arianna Mencattini , Luca Businaro , Eugenio Martinelli , Paolo Bisegna , Alessandro Travaglini , Federica Caselli

Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma.

Journal of experimental & clinical cancer research : CR

Avec: Valeria Lucarini , Ombretta Melaiu , Silvia D'Amico , Fabio Pastorino , Patrizia Tempora , Marco Scarsella , Marco Pezzullo , Adele De Ninno , Valentina D'Oria , Michele Cilli , Laura Emionite , Paola Infante , Lucia Di Marcotullio , Maria Antonietta De Ioris , Giovanni Barillari , Rita Alaggio , Luca Businaro , Mirco Ponzoni , Franco Locatelli , Doriana Fruci

Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.

Nature immunology

Avec: Martina Musella , Andrea Guarracino , Nicoletta Manduca , Claudia Galassi , Eliana Ruggiero , Alessia Potenza , Ester Maccafeo , Gwenola Manic , Luca Mattiello , Sara Soliman Abdel Rehim , Michele Signore , Marco Pietrosanto , Manuela Helmer-Citterich , Matteo Pallocca , Maurizio Fanciulli , Tiziana Bruno , Francesca De Nicola , Giacomo Corleone , Anna Di Benedetto , Cristiana Ercolani , Edoardo Pescarmona , Laura Pizzuti , Francesco Guidi , Francesca Sperati , Sara Vitale , Daniele Macchia , Massimo Spada , Giovanna Schiavoni , Fabrizio Mattei , Adele De Ninno , Luca Businaro , Valeria Lucarini , Laura Bracci , Eleonora Aricò , Giovanna Ziccheddu , Francesco Facchiano , Stefania Rossi , Massimo Sanchez , Alessandra Boe , Mauro Biffoni , Ruggero De Maria , Ilio Vitale , Antonella Sistigu

Kinetic Detection of Apoptosis Events Via Caspase 3/7 Activation in a Tumor-Immune Microenvironment on a Chip.

Methods in molecular biology (Clifton, N.J.)

Avec: Francesca Romana Bertani , Farnaz Dabbagh Moghaddam , Cristiano Panella , Sara Maria Giannitelli , Valentina Peluzzi , Annamaria Gerardino , Alberto Rainer , Giuseppe Roscilli , Adele De Ninno , Luca Businaro

IL-33 stimulates the anticancer activities of eosinophils through extracellular vesicle-driven reprogramming of tumor cells.

Journal of experimental & clinical cancer research : CR

Avec: Adriana Rosa Gambardella , Caterina Antonucci , Cristiana Zanetti , Francesco Noto , Sara Andreone , Davide Vacca , Valentina Pellerito , Chiara Sicignano , Giuseppe Parrottino , Valentina Tirelli , Antonella Tinari , Mario Falchi , Adele De Ninno , Luca Businaro , Stefania Loffredo , Gilda Varricchi , Claudio Tripodo , Claudia Afferni , Isabella Parolini , Fabrizio Mattei , Giovanna Schiavoni

Réseau de co-auteurs

Luca Businaro 18 collaborations

Adele De Ninno 16 collaborations

Giovanna Schiavoni 7 collaborations

Fabrizio Mattei 7 collaborations

Federica Caselli 6 collaborations

Paolo Bisegna 6 collaborations

Riccardo Reale 5 collaborations

Arianna Mencattini 4 collaborations

Eugenio Martinelli 4 collaborations

Francesca Romana Bertani 3 collaborations

Annamaria Gerardino 3 collaborations

A Mencattini 3 collaborations

D Di Giuseppe 3 collaborations

P Casti 3 collaborations

C Di Natale 3 collaborations

E Martinelli 3 collaborations

Sara Andreone 3 collaborations

Valeria Lucarini 3 collaborations

Martina Musella 2 collaborations

Claudia Galassi 2 collaborations

Antonella Sistigu 2 collaborations

Farnaz Dabbagh Moghaddam 2 collaborations

Giovanni Barillari 2 collaborations

Ombretta Melaiu 2 collaborations

M C Comes 2 collaborations

F Corsi 2 collaborations

L Ghibelli 2 collaborations

M C Parrini 2 collaborations

Francesca R Bertani 2 collaborations

Jacopo Mancini 2 collaborations

Antonella Tinari 2 collaborations

Adriana Rosa Gambardella 2 collaborations

Giovanna Ziccheddu 2 collaborations

Isabella Parolini 2 collaborations

Cristiana Zanetti 2 collaborations

Claudia Afferni 2 collaborations

A De Ninno 2 collaborations

Simone Ielpo 1 collaboration

Francesca Barberini 1 collaboration

Silvia Pesce 1 collaboration

Chiara Cencioni 1 collaboration

Francesco Spallotta 1 collaboration

Emanuela Marcenaro 1 collaboration

Roberto Bei 1 collaboration

Loredana Cifaldi 1 collaboration

F R Bertani 1 collaboration

Luigi Racioppi 1 collaboration

Erik R Nelson 1 collaboration

Wei Huang 1 collaboration

Debarati Mukherjee 1 collaboration

Scott A Lawrence 1 collaboration

William Lento 1 collaboration

Anna Maria Masci 1 collaboration

Yiquin Jiao 1 collaboration

Sunghee Park 1 collaboration

Brian York 1 collaboration

Yaping Liu 1 collaboration

Amy E Baek 1 collaboration

David H Drewry 1 collaboration

William J Zuercher 1 collaboration

Joseph Geradts 1 collaboration

Allison Hall 1 collaboration

Anthony R Means 1 collaboration

Nelson Chao 1 collaboration

Ching-Yi Chang 1 collaboration

Donald P McDonnell 1 collaboration

Francesca Spadaro 1 collaboration

Carla Buccione 1 collaboration

Paola Sestili 1 collaboration

Maria Teresa D'Urso 1 collaboration

Maria Colomba Comes 1 collaboration

J Filippi 1 collaboration

M D'Orazio 1 collaboration

F Mattei 1 collaboration

G Schiavoni 1 collaboration

Cassandra Troiano 1 collaboration

Bruno Casciaro 1 collaboration

Francesco Riccitelli 1 collaboration

Yoonkyung Park 1 collaboration

Renato Massoud 1 collaboration

Maria Luisa Mangoni 1 collaboration

Lorenzo Stella 1 collaboration

Flavia Mazzarda 1 collaboration

Annunziata D'Elia 1 collaboration

Roberto Massari 1 collaboration

Gaia Ziraldo 1 collaboration

Veronica Zorzi 1 collaboration

Chiara Nardin 1 collaboration

Chiara Peres 1 collaboration

Francesco Chiani 1 collaboration

Abraham Tettey-Matey 1 collaboration

Marcello Raspa 1 collaboration

Ferdinando Scavizzi 1 collaboration

Alessandro Soluri 1 collaboration

Anna Maria Salvatore 1 collaboration

Jun Yang 1 collaboration

Fabio Mammano 1 collaboration

Alessandro Giovinazzo 1 collaboration

Claudia Matteucci 1 collaboration

Corrado Di Natale 1 collaboration

F Mermet-Meillon 1 collaboration

Michele DaOrazio 1 collaboration

Maria A Brighetti 1 collaboration

Alessandro Travaglini 1 collaboration

Silvia D'Amico 1 collaboration

Fabio Pastorino 1 collaboration

Patrizia Tempora 1 collaboration

Marco Scarsella 1 collaboration

Marco Pezzullo 1 collaboration

Valentina D'Oria 1 collaboration

Michele Cilli 1 collaboration

Laura Emionite 1 collaboration

Paola Infante 1 collaboration

Lucia Di Marcotullio 1 collaboration

Maria Antonietta De Ioris 1 collaboration

Rita Alaggio 1 collaboration

Mirco Ponzoni 1 collaboration

Franco Locatelli 1 collaboration

Doriana Fruci 1 collaboration

Andrea Guarracino 1 collaboration

Nicoletta Manduca 1 collaboration

Eliana Ruggiero 1 collaboration

Alessia Potenza 1 collaboration

Ester Maccafeo 1 collaboration

Gwenola Manic 1 collaboration

Luca Mattiello 1 collaboration

Sara Soliman Abdel Rehim 1 collaboration

Michele Signore 1 collaboration

Marco Pietrosanto 1 collaboration

Manuela Helmer-Citterich 1 collaboration

Matteo Pallocca 1 collaboration

Maurizio Fanciulli 1 collaboration

Tiziana Bruno 1 collaboration

Francesca De Nicola 1 collaboration

Giacomo Corleone 1 collaboration

Anna Di Benedetto 1 collaboration

Cristiana Ercolani 1 collaboration

Edoardo Pescarmona 1 collaboration

Laura Pizzuti 1 collaboration

Francesco Guidi 1 collaboration

Francesca Sperati 1 collaboration

Sara Vitale 1 collaboration

Daniele Macchia 1 collaboration

Massimo Spada 1 collaboration

Laura Bracci 1 collaboration

Eleonora Aricò 1 collaboration

Francesco Facchiano 1 collaboration

Stefania Rossi 1 collaboration

Massimo Sanchez 1 collaboration

Alessandra Boe 1 collaboration

Mauro Biffoni 1 collaboration

Ruggero De Maria 1 collaboration

Ilio Vitale 1 collaboration

Cristiano Panella 1 collaboration

Sara Maria Giannitelli 1 collaboration

Valentina Peluzzi 1 collaboration

Alberto Rainer 1 collaboration

Giuseppe Roscilli 1 collaboration

Caterina Antonucci 1 collaboration

Francesco Noto 1 collaboration

Davide Vacca 1 collaboration

Valentina Pellerito 1 collaboration

Chiara Sicignano 1 collaboration

Giuseppe Parrottino 1 collaboration

Valentina Tirelli 1 collaboration

Mario Falchi 1 collaboration

Stefania Loffredo 1 collaboration

Gilda Varricchi 1 collaboration

Claudio Tripodo 1 collaboration